Loratadine is anti-allergic formulation which is prescribed to be used for treatment of hives and allergic rhinitis. It belongs to second-generation antihistamine class of medication and shows complete 100% of bioavailability. This compound serves as inverse agonist to histamine H1 receptors thus reducing allergic conditions. It shows protein binding ability of about 97 to 99% with elimination half life of 8 hours. Loratadine gets metabolized in liver with help of CYP2D6 & CYP3A4 enzymes and assures targeted mode of action. It is also considered perfect for providing relief from chronic idiopathic urticaria and skin allergies.